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Inside of a current review, we noted the identification plus the characterization of a completely new atypical opioid receptor with special destructive regulatory Qualities towards opioid peptides.1 Our final results showed that ACKR3/CXCR7, hitherto referred to as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is also a broad-spe